Human embryonal prealbumin-1. Chemical and immunochemical characteristics

Pavlenko, A.F.; Bulgakov, A.A.; Belogortseva, N.I.; Ovodov, I.S.

Bioorganicheskaia Khimiia 15(6): 731-736

1989


ISSN/ISBN: 0132-3423
PMID: 2783171
Document Number: 328866
General chemical and immunochemical characterization of human embryonic prealbumin-1 (EPA-1) isolated from abortive blood is presented. EPA-1 was found to exist as glycosylated and non-glycosylated forms, which are immunochemically identical. Sugar moiety of the glycosylated form contains residues of fucose (3.0%), mannose (3.2%), galactose (7.8%), N-acetylglucosamine (5.4%), N-acetylgalactosamine (1.2%) and N-acetylneuraminic acid. Using methylation studies, types of bonds between the sugar residues were elucidated.

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