Localization of human prealbumin in ciliary epithelium and retina

Inada, K.

Nippon Ganka Gakkai Zasshi 92(5): 741-745

1988


ISSN/ISBN: 0029-0203
PMID: 2461063
Document Number: 320959
Aqueous humor has several serum proteins and the concentration of each of the proteins is very low in normal eyes. The aqueous/serum ratio of prealbumin was reported to be higher than those of other human aqueous proteins in a previous paper. To investigate the possibility of synthesis of prealbumin, human eyes were examined using the peroxidase-antiperoxidase method. The immunohistochemical survey revealed the presence of prealbumin in the non-pigmented layer of the ciliary epithelium and the ganglion cell layer of the retina. Some cells situated on the inner side of the internal nuclear layer of the retina also showed staining. This study demonstrated the possibility of synthesis of prealbumin in human eye by immunohistochemistry.

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