Macrophage activation and Mycobacterium leprae: effect of interferon gamma on the production of oxygen free radicals by phagocytic cells

Launois, P.; Dieye, A.; Blum, L.; Millan, J.; Sarthou, J.L.

Dakar Medical 34(1-4): 78-82

1989


ISSN/ISBN: 0049-1101
PMID: 2518818
Document Number: 327647
Activation of the respiratory metabolic channel (F.O.R.), responsible in part for the bactericidal effect, was measured in vitro by a chemoluminescence test on circulating phagocytes. All mycobacteria tested, except for Mycobacterium leprae, induced a significant response. Its effect on lepromatous leprosy pathology is a subject for discussion.

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