Experimental chemotherapy of alveolar hydatid disease. 12. the efficacy of drug forms of mebendazole and nocodazole with high bioavailability
Dzhabarova, V.I.; Dobrotvorskiĭ, A.E.; Krotov, A.I.
Meditsinskaia Parazitologiia i Parazitarnye Bolezni 5: 43-46
1989
ISSN/ISBN: 0025-8326 PMID: 2615711 Document Number: 327277
New formulations have been designed to increase the efficacy and bioavailability of the oral drugs mebendazole and nocodazole and were tested in CBA mice. A considerable increase in efficacy was established for a solid disperse formulation of certain composition with a relatively lower toxicity than in aqueous suspensions of the drugs.