Stimulation of energy plastic metabolism by phytohemagglutinin in lymphoid organs and adrenal glands
Soroka, V.R.; Anisimova, V.P.
Ukrainskii Biokhimicheskii Zhurnal 61(4): 42-47
1989
ISSN/ISBN: 0201-8470 PMID: 2555946 Document Number: 326596
It has been established that the concentration of nucleic acids, protein, glycogen, ATP, copper, manganese, zinc as well as the activity of cytochromoxidase and succinate dehydrogenase in tissues of the thymus gland and spleen of albino rats a day after stimulation by phytohemagglutinin increase considerably reaching the maximal values three days later. Taking a prolonged term (up to 7 days) after phytohemagglutinin administration it is found that the content and activity of the studied indices in the thymus and spleen tissues lower regularly, but fail reaching normal values even 14 days after stimulation. In this case changes in the test indices in the spleen are less pronounced than in the thymus in all the studied periods. In the tissues of adrenals a tendency of changes in the manganese and copper content is like that in lymphoid organs in all periods after stimulation by phytohemagglutinin; other test indices have an opposite tendency.