Low levels of chloroquine resistance of Plasmodium falciparum in the province of Zou in Benin
Djivoh, C.; Massougbodji, A.; Turk, P.; Fayomi, E.B.; Gay, F.; Danis, M.
Bulletin de la Societe de Pathologie Exotique et de Ses Filiales 81(3): 332-337
1988
ISSN/ISBN: 0037-9085 PMID: 3052897 Document Number: 325100
An in vivo test using the WHO protocol (chloroquine 25 mg/kg within 3 days, trial over 7 days) was performed in 72 children in the province of Zou, Benin, in July-August 1987. The blood concentration of chloroquine was dosed before, during and after treatment by a sensitive method. This study showed a low rate of drug resistance (4.2%), even though surveys in Cotonou exhibited a high level of chloroquine resistance.