A new specific chromosomal rearrangement, t (11;20) (p15;q11) , in myeloblastic leukemia with maturation
Mitelman, F.; Prigogina, E.L.; Fleischman, E.W.; Frenkel, M.A.; Garwicz, S.; Heim, S.; Ilyinskaya, G.W.; Kristoffersson, U.; Mandahl, N.; Volkova, M.A.
Leukemia 2(7): 430-432
1988
ISSN/ISBN: 0887-6924 PMID: 3164800 Document Number: 322152
The translocation t(11;20)(p15;q11) was found as the sole acquired clonal chromosome abnormality in two patients with acute myeloid leukemia. The bone marrow morphology in both cases corresponded to the M2 subtype of the French-American-British (FAB) classification. None of the patients achieved complete remission, and both died less than 6 months after diagnosis. This particular translocation has not previously been reported in acute nonlymphocytic leukemia.