Further studies on the rise and decline of Plasmodium vivax gametocyte viability
Yang, B.L.
Zhonghua Liu Xing Bing Xue Za Zhi 9(6): 329-331
1988
ISSN/ISBN: 0254-6450 PMID: 3073015 Document Number: 321207
This paper deals with the infectivity of gametocytes for A. sinensis in two cases artificially infected with vivax malaria. The results obtained in this study indicated that the mosquitoes have become infected on the first day of illness and that the percentage of infected mosquitoes came to a peak on 2 to 8 days after the first appearance of clinical signs. Following this the infectivity declined obviously. The average oocyst count tends to reach its peak in each participant on 3 to 6 days, after which on day 7 it falls abruptly and remains fairly low without fluctuation until the acute symptoms subside by immune response of the host. We suggested that the data recorded here provide the most favorable time to obtain P. vivax infection in mosquitoes and this information has been of value in experimental investigations where a large number of sporozoites were required.