Morphofunctional characteristics of Clara cells in hypoxia in rats from the data of scanning and transmission electron microscopy
Tsagareli, Z.G.; Gogiashvili, L.E.; Sadunshvili, M.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 106(9): 363-365
1988
ISSN/ISBN: 0365-9615 PMID: 3167194 Document Number: 320598
The experiments on the model of altitude-chamber hypoxia in rats have established that within 15 days the secretory activity of terminal bronchiolar Clara cells increased in the secret accumulation phase and was accompanied by the transformation of the apical surface relief and ultrastructure of synthetic cell apparatus. Chronic hypoxia lasting for up to 60 days leads to compensation-adaptation changes of Clara cell ultrastructure, providing the intensification of secretion processes and postsecretion repair of membranes of the apical surface cells.