Effect of carnosine on intraocular pressure
Ermakova, V.N.; Babizhaev, M.A.; Bunin, A.Ia.
Biulleten' Eksperimental'noi Biologii i Meditsiny 105(4): 451-453
1988
ISSN/ISBN: 0365-9615 PMID: 3359028 Document Number: 317941
It has been demonstrated in experiments on non-anesthetized rabbits that conjunctival injection of carnosine (beta-alanyl 1-histidine) caused a decrease in normal intraocular pressure and reduced prostaglandin-induced ocular hypertension. The rapid onset of the pressure response and the absence of papillary dilation in rabbits treated with carnosine were observed. It is concluded that L-carnosine can be used as a potent drug for the prevention of reactive hypertension syndrome.