The cure rates of patients infected with heterophyiasis and treated with praziquantel versus niclosamide
el-Hawy, A.M.; Safwat, M.; el-Nasr, S.S.; Abdel Rahman, M.M.
Journal of the Egyptian Society of Parasitology 18(2): 437-442
1988
ISSN/ISBN: 1110-0583 PMID: 3418143 Document Number: 315875
83 heterophyiasis patients were classified in 5 groups and given praziquantel orally in doses of 40 mg/kg body weight t.d.s. for one day, 40 mg/kg body weight as a single dose, 25 mg/kg body weight t.d.s. for 2 successive days, 20 mg/kg body weight as a single dose and 10 mg/kg body weight as a single dose. Other 40 patients were given niclosamide 2 gm orally every other day for three doses. Praziquantel in the doses given in the first four groups gave 100% cure rate (P < 0.05), the niclosamide group gave 77.5% cure rate. Praziquantel in single dose of 20 mg/kg body weight orally is more superior and tolerated than niclosamide.