Use of the oral glucose tolerance curve as a criterion for validating some indicators of risk of developing glucose intolerance
González Bernal, G.; Avila Rosas, H.; Breña Flores, H.
Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 40(3): 259-264
1988
ISSN/ISBN: 0034-8376 PMID: 3217617 Document Number: 313822
Results from previous studies with non-pregnant women suggest that glucose intolerance can be predicted in those who have 1-h postprandial glucose values (PPG) 130 mg/100 ml or more and in those who have 2-h PPG 150 mg/100 ml or more. In this study, 100 non-pregnant women with 1-h PPG 130 mg/100 ml or more were assessed for 2-h PPG 150 mg/100 ml or more and 3-h PPG 178 mg/100 ml or more. Other risk factors for glucose intolerance were also evaluated including a family history of diabetes mellitus, age of 33 years or older, overweight by 127% of ideal body weight or more, and 4 or more pregnancies. Of the 100 women with a 1-h PPG 130 mg/100 ml or more, 58 had a 2-h PPG 150 mg/100 ml or more, and 27 had a 3-h PPG 178 mg/100 ml or more. Glucose tolerance was then assessed in all the women using the oral glucose tolerance test. Results showed that 78% of women with PPG 130 mg/100 ml or more, 76% of women with PPG 150 mg/100 ml or more and 82% of women with PPG 178 mg/100 ml or more showed glucose intolerance. At all PPG values, the greatest correlations of risk for glucose intolerance were with overweight and age.