Top Abstract Purchase Related
Home
>
Node
>
Subnode

A commercial pregnancy test modified for field studies of fetal loss

Holman, D.J.; Rasheed, F.N.; Stroud, C.M.; Brindle, E.; O'connor, K.A.; Campbell, K.L.

Clinica Chimica Acta; International Journal of Clinical Chemistry 271(1): 25-44

1998

ISSN/ISBN: 0009-8981
PMID: 9564555
DOI: 10.1016/s0009-8981(97)00225-8
Document Number: 313681
We describe simple modifications to the ICON II hCG (URINE) pregnancy test to provide a sensitive and specific urinary assay for hCG in field studies of fetal loss. The modified assay had a qualitative lower limit of detection of 0.30 IU/l, a 50% qualitative limit of 0.61 IU/l, a 100% qualitative limit of 1.16 IU/l, and a quantitative limit of 0.80 IU/l. Coefficients of variation ranged from 9.9% to 21.1%. Parallelism was observed among serially diluted subject samples. We used the assay in an 11-month prospective study of fetal loss in rural Bangladesh in which urine samples were collected twice-weekly from 494 women; 330 pregnancies and 93 fetal losses were detected. The median time to a positive pregnancy diagnosis was day 26 from last menses. The modified assay provided qualitative detection of early pregnancy comparable to laboratory assays, and appears to be well suited for use in epidemiologic or rural-population fetal loss studies.

Document emailed within 0-6 h
Secure & encrypted payments

Hajeri, H.; Winisdoerffer, G.; Philippe, E.; Beauvais, P.; Dreyfus, J. 1972: Detection of chronic fetal suffering during pregnancy toxemia. Comparative value of urinary estriol determination and of a test of fetal tolerance to uterine contraction Journal de Gynecologie Obstetrique et Biologie de la Reproduction 1(6): 593-594
Crimail, P.; Luciani, M. 1972: Fetal heart rate during pregnancy. Oxytocin test and atropine test Revue Francaise de Gynecologie et d'Obstetrique 67(12): 749-761
Paublo, M.A.; Aitken, S.; Atala, C. 1987: Usefulness of the modified fetal biophysical profile in intrahepatic cholestasis of pregnancy Revista Chilena de Obstetricia y Ginecologia 52(5): 296-303
Matthews, A.L. 1990: Known fetal malformations during pregnancy: a human experience of loss Birth Defects Original Article Series 26(3): 168-175
Neumann, G.; Gartzke, J.; Faber, G. 1978: Evaluation of fetal lung maturity using a modified lecithin-sphingomyelin determination and Clements' foam test Zentralblatt für Gynakologie 100(19): 1240-1244
Querleu, D.; Boutteville, C.; Renard, X.; Crépin, G. 1984: Diagnostic evaluation of fetal distress during pregnancy by a sound stimulation test Journal de Gynecologie Obstetrique et Biologie de la Reproduction 13(7): 789-796
Nagamine, T.; Asahara, T.; Ide, S.; Yoshimura, M.; Igarashi, Y. 1975: Studies on a test vaccine for equine influenza virus. II. Field trials Kitasato Archives of Experimental Medicine 48(2-3): 69-82
Archer, J.F.; Beverley, J.K.; Watson, W.A.; Hunter, D. 1971: Further field studies on the fluorescent antibody test in the diagnosis of ovine abortion due to toxoplasmosis Veterinary Record 88(7): 178-180
Fior, R.; Tamburini, P. 1985: Screening studies with the BOEL test for the early diagnosis of hearing loss in infants. Experiences with 4,622 cases Laryngologie Rhinologie Otologie 64(5): 260-262
Daffos, F.; Forestier, F.; Nahoul, K.; Castanier, M.; Capella-Pavlovsky, M.; Chartier, M.; Scholler, R. 1984: Fetal hormonology by direct sampling of fetal blood during the 2d trimester of pregnancy. Study of fetal and maternal 5-ene steroid sulfates Pathologie-Biologie 32(8): 891-894
Snyder, H.; Yeldandi, V.V.; Prem Kumar, G.; Liao, C.; Lakshmi, V.; Gandham, S.R.; Muppudi, U.; Oruganti, G.; Schneider, J.A. 2012: Field-based video pre-test counseling, oral testing, and telephonic post-test counseling: implementation of an HIV field testing package among high-risk Indian men Aids Education and Prevention: Official Publication of the International Society for Aids Education 24(4): 309-326
Allocca, G.; Tramontana, S.; Chiantera, A. 1971: Histochemical studies of steroidogenesis of the fetal appendages in pregnancy. (Preliminary note) Minerva Ginecologica 23(15): 651-652
Pałys, B.; Baszczyńska, J.; Jańczyk, Z. 1982: Coagulation studies of pregnancy complicated by EPH gestosis with coexistent fetal dystrophy Ginekologia Polska 53(4): 257-261
Cheng, X.-y.; Zhang, L.-j.; Lin, L.; Liu, J.; Ding, Y.-l. 2009: Relationship of fetal total bile acid and the change of fetal pancreas endocrine secretion and its impact on fetal growth and development in intrahepatic cholestasis of pregnancy Zhonghua Fu Chan Ke Za Zhi 44(1): 23-26
Fretts, R.C. 2001: Maternal age and fetal loss. Older women have increased risk of unexplained fetal deaths Bmj 322(7283): 430
Dobrotina, A.F.; Darovskaia, M.G.; Tret'iakova, E.V.; Strukova, V.I. 1980: Prognostic value of hormonal studies of the amniotic fluid in pregnancy with a high fetal risk Akusherstvo i Ginekologiia 2: 37-38
Resch, B.A.; Papp, J.G.; Herczeg, J. 1979: Normal values of fetal heart rate in the 5th to 18th weeks of pregnancy (in vivo and in vitro studies) Zentralblatt für Gynakologie 101(1): 29-34
Adachi, M.; Shirato, S. 1994: The usefulness of the Noise-Field Test as a screening method for visual field defects Japanese Journal of Ophthalmology 38(4): 392-399
Engelke, J.; Feldmann, M.; Gundling, N.; Gundelach, Y.; Egli, C.; Hoedemaker, M.; Piechotta, M. 2015: Pregnancy diagnosis by detection of pregnancy-associated glycopoteins in milk: evaluation of a commercial available ELISA Berliner und Munchener Tierarztliche Wochenschrift 128(9-10): 402-408
Jochle, W.; Gunzler, O. 1976: Effects of gestagens on the early phases of pregnancy in cattle--clinical experiences. 3. 2 double-blind studies under field conditions: attempt at comparative discussion Deutsche Tierärztliche Wochenschrift 83(4): 155-158