Age-related reference values for free amino acids in first morning urine specimens
Parvy, P.R.; Bardet, J.I.; Rabier, D.M.; Kamoun, P.P.
Clinical Chemistry 34(10): 2092-2095
1988
ISSN/ISBN: 0009-9147 PMID: 3168222 Document Number: 313062
We determined age-related reference values for urinary free amino acids (in mmol/mol creatinine) in first morning urine specimens from 360 control subjects who were divided into nine age groups: birth to 1 month, 1-6 months, 6-12 months, 1-2 years, 2-4 years, 4-7 years, 7-10 years, 10-13 years, and older than 13 years. Except for taurine and 3-methylhistidine, the concentration of all the amino acids decreased with increasing age. The use of these results to detect aminoacidopathies and tubulopathies is discussed.