Structural changes in hepatocytes during rheopolyglucine administration and subsequent stress in mice
Shkurupiĭ, V.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 105(5): 613-616
1988
ISSN/ISBN: 0365-9615 PMID: 2454687 Document Number: 310157
A lysosomotropic agent rheopolyglucine was injected intravenously to male CBA mice at a dose of 1 ml per 100 g body weight. Two hours later hepatocyte hypertrophy and cytoplasmic organoid hyperplasia were observed. The exposure of these mice to acute stress did not lead to catabolic changes in hepatocytes.
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