High-risk factors for cervical cancer. An epidemiological study in SWA/Namibia

Bloch, B.; Homer, L.; Orford, H.J.; Roberts, M.A.; Bloch, B; Homer, L; Orford, H.J; Roberts, M.A

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High-risk factors for cervical cancer. An epidemiological study in SWA/Namibia

Bloch, B.; Homer, L.; Orford, H.J.; Roberts, M.A.

South African Medical Journal 74(6): 284-289

1988

ISSN/ISBN: 0256-9574

PMID: 2843990

Document Number: 309909

An epidemiological study was carried out in SWA/Namibia to document the prevalence of high-risk factors for cervical cancer among 754 women belonging to several ethnic groups and from both urban and rural areas: 75.6% of the women were aged <35 years, 62.5% were <18 years of age at first intercourse, 65% had had 2 sexual partners, and there was a high incidence of sexually transmitted diseases (59.7% women were positive for syphilis by the TPHA). Cytological examination demonstrated that 53 of 684 (7.7%) women had cervical abnormalities and 24% had evidence of human papillomavirus (HPV) infection. The highest incidence of HPV infection and of cervical intra-epithelial neoplasia was seen in the same age-groups, 20-29 and 30-39 years. All 754 women had antibodies to herpes simplex virus (HSV) and 451 of 452 women had antibodies to HSV type 2. Four of 217 sera obtained from women from the northern regions had antibodies to HTLV-I, 1 had antibodies to simian immunodeficiency virus (SIVmac) and none had antibodies to HIV-1. [Serological results should be interpreted with caution perhaps, as details of the tests used have not been provided in this paper.].

High-risk factors for cervical cancer. An epidemiological study in SWA/Namibia

Bloch, B.; Homer, L.; Orford, H.J.; Roberts, M.A.

South African Medical Journal 74(6): 284-289

1988

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