Zinsser-Engman-Cole syndrome (dyskeratosis congenita) in a 13-year-old boy
Kopyść, Z.; Jankowska-Skrzypek, A.; Bielniak, J.; Sokołowska, B.; Grochowina, T.
Wiadomosci Lekarskie 41(8): 525-530
1988
ISSN/ISBN: 0043-5147 PMID: 3239051 Document Number: 309358
A 13-year-old boy is reported with a rarely observed full syndrome of Zinsser-Engman-Cole (reticular hyperpigmentation, atrophy, depigmentation, telangiectasiae, mucosal focal leucoplakia, hyperkeratotic foci, abnormalities of hair growth and teeth) with coexistent disturbances of psychophysical development and bilateral cryptorchism. The authors stress an infrequently observed location of the neoplastic focus (hyperkeratotic lesion on plantar skin and not a leucoplakia focus on the mucosa), absence in the observed case of haematological disturbances frequently occurring in the syndrome, and the possibility of a causal relationship between the discussed syndrome and the character of occupation of the father before boirth of the boy (long-term contact with polychlorine insecticides and herbicides).