Doxycycline esophagitis and esophageal ulcer
Kolarski, V.; Petrova-Shopova, K.; Nikolov, S.; Vasileva, E.; Petrova, D.
Vutreshni Bolesti 27(1): 63-67
1988
ISSN/ISBN: 0506-2772 PMID: 3414086 Document Number: 308858
Four cases of acute doxycycline injury of the esophageal mucosa--acute catarrhal doxycycline esophagitis and acute doxycycline ulcer are presented. The pathogenesis, clinical course, endoscopic pattern, prophylaxis and treatment of these complications of doxycycline treatment are discussed in detail. The gastroesophageal and duodenogastric reflux, which are most often the result of functional failure of the lower esophageal sphincter, are pointed out as the basic pathogenetic mechanism of the esophageal mucosa injury in oral doxycycline treatment.