Esophageal epithelial cells renewal in evaluation of the pariet efficacy in the treatment of patients with reflux esophagitis
Osadchuk, M.A.; Lipatova, T.E.; Chaplygin, N.V.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 4: 23-26; 131
2002
ISSN/ISBN: 1682-8658 PMID: 12503269 Document Number: 548637
The article provides the data on 20 patients with erosive reflux esophagitis, who were treated with Pariet (rabeprazole). It was shown on the basis of conducted clinical endoscopic, morphological and immunohistochemical studies that the application of Pariet in treatment of patients with erosive esophagitis contributes to clinical endoscopic remission, regression of inflammatory changes, recovery of apoptosis processes and proliferative activity of esophagus epithelial cells within a shorter period of time. The results of the observation allow recommending Pariet as a highly efficient preparation for treatment of patients with gastroesophageal reflux disease.