Effect of stress conditions on the course of trophozoite-induced Plasmodium yoelii nigeriensis in mice recently cured of a previous infection

Oyerinde, J.P.; Fagbenro-Beyioku, A.F.; Jaji, B.E.

African Journal of Medicine and Medical Sciences 17(2): 97-100

1988


ISSN/ISBN: 0309-3913
PMID: 2843024
Document Number: 308534
The effect of stress conditions on the course of trophozoite-induced Plasmodium yoelii nigeriensis in mice recently treated for a previous infection was studied. It was found that when the mice were infected with up to 5943 parasites within 6 days of treating a previous infection, no patent infection was recorded. However, an inoculum of 7924 parasites induced parasitaemia, with a long period of prepatency and a short course of infection before the parasites died out. None of the mice re-infected with the parasite, and maintained at different temperatures, was positive during the period of the experiment.

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