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Effect of single 60Co whole-body irradiation on the absolute count and degree-of-maturity distribution of reticulocytes in the rat

Becker, K.J.; Eder, H.; Wiemer, U.

Strahlentherapie und Onkologie Organ der Deutschen Rontgengesellschaft . 163(11): 748-752

1987

ISSN/ISBN: 0179-7158
PMID: 3317952
Document Number: 302274
Wistar-rats were exposed to a single 60Co-gamma-total body irradiation with 1.5 Gy, 3.0 Gy and 4.5 Gy. The trend of reticulocyte count and the reticulocyte maturation distribution were measured with an automatic analysis system over a period of 30 days. In all animals the reticulocyte count as well as the maturation distribution showed minima at the second and the twelfth day post irradiation. The duration of the minima were dose dependent. The changes of the reticulocyte count and the maturation distribution are equivalent.

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