In vitro evaluation of teicoplanin and other antimicrobials against streptococci group D bacteria
Breyer, S.; Georgopoulos, A.; Graninger, W.
Drugs under Experimental and Clinical Research 13(8): 479-481
1987
ISSN/ISBN: 0378-6501 PMID: 2962843 Document Number: 300407
In vitro activities of teicoplanin were compared with those of ampicillin, imipenem, rifampicin, coumermycin and vancomycin against clinical isolates of Streptococcus faecalis (n = 100) and Streptococcus faecium (n = 30). Against Str. faecalis, ampicillin and imipenem had an MIC90 and MBC90 of 3.9 micrograms/ml. Coumermycin and rifampicin had poor bactericidal activity with MBC90 values of 31.2 and 62.5 micrograms/ml. Teicoplanin was extremely active with an MIC90 of 0.95 microgram/ml and an MBC90 of 1.86 micrograms/ml.