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Rotavirus persistence in malabsorption syndrome: virus assessment by immunofluorescence in small intestine biopsies in relation to antibody titres

Körting, H.J.; Fiehring, C.; Senkpiel, K.; Körting, L.

Acta Virologica 31(1): 31-35

1987

ISSN/ISBN: 0001-723X
PMID: 2883855
Document Number: 300025
Results of quantitative immunofluorescence (IF) in small intestine biopsies and the serum antibody titres as detected by indirect RotalexR test in rotavirus infections were compared using regression and correlation analysis. Based on the significance of the statistically established correlation (r = 0.76; n = 30) between immunohistological identification of rotavirus antigen and determination of serum antibody levels, the indirect RotalexR test may be applied as a diagnostic tool to avoid biopsies in productive rotavirus persistence.

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