Morphofunctional state of the hypothalamic-pituitary neurosecretory system of rats flown on Cosmos-1667
Alekseev, E.I.
Kosmicheskaia Biologiia i Aviakosmicheskaia Meditsina 21(6): 27-31
1987
ISSN/ISBN: 0321-5040 PMID: 3437736 Document Number: 298303
Morphological and morphometric data were used for comparative analysis of changes in the major compartments of the hypothalamic-pituitary neurosecretory system of Cosmos-1667 experimental and control rats. The flown rats showed morphological signs of inhibited ADH production. This inhibition may facilitate fluid excretion and development of a new hydration level at an early stage of adaptation to microgravity. The enhanced ADH secretion from neurons of supraoptic nuclei of the hypothalamus and axons of the posterior pituitary may lead to water retention and compensation of water loss after return to Earth's gravity.