Morphometric study of the effect of 5-hydroxytryptophan on the activity of various hypothalamic centers in rats depending on the state of their sexual system
Danilova, O.A.; Ali, K.M.
Problemy Endokrinologii 26(4): 42-46
1980
ISSN/ISBN: 0375-9660 PMID: 6968067 Document Number: 155946
The effect of 5-oxytryptophan (serotonin metabolic precursor), injected intraperitoneally to female rats (intact and with deafferented mediobasal hypothalamus) on the activity of a number of hypothalamic centres was studied. The activity of cells, both outside and inside the isolated area, proved to alter under the effect of 5-oxytryptophan. The direction of these effects depends on the initial state of the hypothalamic centres and on the hormone in whose presence serotonin acts.