Treatment of nasopharyngeal cancer with recombinant gamma interferon (IFN) . A report based on 2 patients
Zanetti, F.; Elies, S.
Laryngologie Rhinologie Otologie 66(1): 54-56
1987
ISSN/ISBN: 0340-1588 PMID: 3104706 Document Number: 298215
Patients with advanced NPC and tumour relapses were efficiently treated with recombined gamma-interferon in some instances. The authors report on two selected cases with elevated EBV titres who belonged to the "high-risk group" and had an unfavourable prognosis. Both patients were treated with gamma-interferon over a period of 6 months and the EBV titres decreased. No relapses have been observed until now. Radiation therapy (RT) is the treatment of choice in NPC. Chemotherapy does not show any advantage in respect of relapse-free survival and overall survival. Interferon seems to be an efficient therapy in selected cases. Questions regarding the effectiveness, the dosage and side effects of the individual classes of interferons are still unclear and should be an important task for further research.