Myocardiopathies of Friedreich's disease
Klein, J.M.; Assyag, P.; du Cailar, G.; Koenig, A.; Chauvin, M.; Brechenmacher, C.
Annales de Cardiologie et d'Angeiologie 36(1): 27-30
1987
ISSN/ISBN: 0003-3928 PMID: 2950821 Document Number: 297824
Cardiac involvement in Friedreich's disease is classically a hypertrophic myocardiopathy, concentric or assymmetrical with or without dilatation. It has nothing specific in comparison to other myocardiopathies. Nevertheless, forms with a dilated myocardiopathy are also possible, but much more unfrequent. A propos of three cases, we have studied the different aspects of myocardiopathies in Friedreich's ataxia. The problem raised by the case of an hypertrophic myocardiopathy evolving toward a dilated form, unusual element of this pathology, is presented. The therapeutic potential of hypertrophic myocardiopathies is classically represented either by beta-blockers or by the more recent slow calcium inhibitors.