Reproduction and differentiation of cells in the tissues of growing rat teeth in response to parathyroid hormone and hydrocortisone
Mazhuga, P.M.; Kabak, K.S.; Zhitnikov, A.I.; Kalion, P.T.
Arkhiv Anatomii Gistologii i Embriologii 92(5): 57-62
1987
ISSN/ISBN: 0004-1947 PMID: 3619678 Document Number: 294206
Influence of parathyroid hormone (PTH) and hydrocortisone (HC) on growth and development of teeth during prefunctional period has been studied, employing radioactive tracers. Biosynthetic and reproductive activity of cells is estimated in the molar and incisor tissues. It has been established that PTH accelerates the process of local resorption of the bone along the alveolar crest, but does not influence upon the teeth growth, functional and reproductive activity of the pulp cells. HC inhibits protein and glycoprotein synthesis, decreases amount of proliferating cells, accelerates their differentiation and, thus, delays formation of the root and tooth growth.