Cytochemical classification of acute lymphoblastic leukemia in children
Gu, Y.X.; Cui, Y.F.; Liu, X.T.; Bai, Y.; Tan, Z.X.; Zhang, D.F.; Lu, S.G.
Chinese Medical Journal 100(8): 663-668
1987
ISSN/ISBN: 0366-6999 PMID: 3129248 Document Number: 293791
By acid phosphatase (ACP), 5-nucleotidase (5'N) activities and PAS reaction patterns, the classification of 31 acute lymphoblastic leukemia (ALL) cases (including 5 adult cases) were studied cytochemically. The results indicated that 16% of the cases were T-ALL, while 84% were nonTnonB-ALL. The results of monoclonal antibody method and E-rosette method were in good accordance with the cytochemical classification. The various forms of ACP activity patterns, PAS reaction, the relationship between the results of monoclonal antibody, E-rosette and cytochemical method and the practical value of ACP activity patterns in the identification of E-rosette negative ALL are discussed.