Immunoglobulin and granulocyte cytochemical reactions in L-asparaginase treated children with acute lymphoblastic leukemia

Zajaczkowski, L.; Pituch, A.; Legutko, L.

Medecine Interne 14(3): 191-195

1976


ISSN/ISBN: 0377-1202
PMID: 1071477
Document Number: 104769
The dose-dependent effect of L-asparaginase (Crasnitin, Bayer) on the serum IgG, IgA and IgM content was studied in 14 children with acute lymphoblastic leukemia. This effect was less evident in the intracellular metabolism of peripheral blood granulocytes (studied by the NBT test), in the myeloperoxidase and alkaline phosphatase activities and in the serum glycogen and lipid content.

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