Physicochemical properties of the diabetogenic factor and its complex with heparin
Kudriashov, B.A.; Ammosova, I.M.; Liapina, L.A.; Ul'ianov, A.M.
Farmakologiia i Toksikologiia 50(3): 49-52
1987
ISSN/ISBN: 0014-8318 PMID: 3609278 Document Number: 293476
The diabetogenic factor (DGF) isolated from the human blood and the blood of rats with diabetes mellitus was shown to be a protein homogeneous at electrophoresis in gel of polyacrylamide, with the molecular weight of 60,000 D. The interaction of DGF with heparin results in the formation of a complex in which the factor's properties are blocked and those of heparin as a anticoagulant are preserved.
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