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Physicochemical properties of 7-phenylacetamidodesacetoxy-cephalosporanic acid

Nys, P.S.; Kol'tsova, E.V.; Shellenberg, N.N.; Zinchenko, E.Ia.; Riabova, N.M.

Antibiotiki 21(4): 309-312

1976

ISSN/ISBN: 0003-5637
PMID: 5950
Document Number: 105039
7-Phenylacetamidodesacetoxycephalosporanic acid was prepared by transformation of benzylpenicillin. The acid was subjected to potentiometric titration and investigation of its electrophoretic mobility at wide pH ranges. The data of the potentiometric titration and electrophoresis were used for calculation of the acid Ki. Minimum solubility of the acid was determined and the curve of its solubility at wide pH ranges was estimated.

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