Maternal administration of indomethacin and neonatal tricuspid insufficiency
Magny, J.F.; Petit, J.; Saby, M.A.; Dehan, M.; Gabilan, J.C.
Archives Francaises de Pediatrie 44(3): 189-190
1987
ISSN/ISBN: 0003-9764 PMID: 3579483 Document Number: 292077
The authors report the case of a neonate who presented since birth with refractory hypoxemia, peripheral edemas, ascites and pleural effusions. The mother had been given indomethacin for the 10 preceding days, in order to avoid premature labour. Echocardiography showed a tricuspid valve dysfunction with important regurgitation in the neonate. Under symptomatic treatment, clinical symptoms disappeared within 10 days. Echocardiography was normal by age 3 months. The responsibility of administration of indomethacin to the mother is discussed.