Neonatal alloimmunothrombocytopenia--effect of combination therapy consisting of I.v. immunoglobulin administration and transfusion of PLA1-negative maternal thrombocytes
Choudhury, A.R.; Friederichs, E.; Speer, C.P.; Schröter, W.
Monatsschrift Kinderheilkunde Organ der Deutschen Gesellschaft für Kinderheilkunde 137(8): 458-462
1989
ISSN/ISBN: 0026-9298 PMID: 2811877 Document Number: 336384
Two newborn infants with severe alloimmunothrombocytopenia due to maternal immunization against fetal PlA1-positive platelets were treated by a combination of i.v.-immunoglobulin (400 mg/kg b.w.) and a transfusion of maternal PlA1-negative platelets. In one infant this regimen was successful; the other one had to be retreated by i.v. immunoglobulin application (400 mg/kg b.w.) over a period of five days.
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