The use of levamisole (decaris) in patients with inoperable lung cancer
Pivniuk, V.M.; Kas'ianenko, I.V.; Pivniuk, N.A.
Voprosy Onkologii 33(5): 82-86
1987
ISSN/ISBN: 0507-3758 PMID: 3495925 Document Number: 290779
Immunologic vigor and the efficacy of combined treatment (short- and long-term courses of levamisole + chemoradiotherapy) were assessed in 195 cases of inoperable epidermoid cancer of the lung. In some cases, lymphocyte response to levamisole in vitro incubation was studied in a reaction of spontaneous rosette formation with ovine erythrocytes prior to therapy. Shorter courses of levamisole used in combination with chemoradiotherapy were followed, on the average, by a 4 months longer survival. The results obtained make the case for studying lymphocyte response to levamisole in vitro in a reaction of spontaneous rosette formation as a criterion for its administration for lung cancer treatment.