Contact allergy to the antifungal agent naftifin
Hoting, E.; Küchmeister, B.; Hausen, B.M.
Dermatosen in Beruf und Umwelt. Occupation and Environment 35(4): 124-127
1987
ISSN/ISBN: 0343-2432 PMID: 2959458 Document Number: 289191
Two patients treated topically against dermatophytes with a naftifine containing antifungal became allergic to the efficacious component naftifine. One of them also reacted to benzyl alcohol. Sensitization experiments in guinea pigs corroborated the suspicion that this allylamine is a contact sensitizer. To date, only few cases of allergic reactions to naftifine have been reported.