The change of carnitine content in seminal plasma after reversible injection occlusion of vas deferens
Qui, Y.; Tian, K.; Yang, D.; Zhang, Q.; Wang, Z.; Huang, Z.; Sun, M.; Mingzhang, S.
Contraception 51(4): 261-263
1995
ISSN/ISBN: 0010-7824 PMID: 7796593 DOI: 10.1016/0010-7824(95)00043-aDocument Number: 288632
The change in carnitine content in seminal plasma after reversible injection occlusion of vas deferens (RIOVD) was observed. RIOVD is a safe, effective and simple method of male fertility control. Carnitine was determined by micro-enzymatic method. The incidence of sperm disappearance increased with the duration of RIOVD and reached 90% at the end of 12 months after operation. Before RIOVD, the mean value of carnitine in seminal plasma was 336.9 +- 78.1 nmol/ml (X +- SD, n = 58); after RIOVD, the mean value of seminal plasma carnitine was 112.7 +- 50.7 nmol/ml (n = 172) in the group with sperm disappearance, and 172.5 +- 71.7 nmol/ml (n = 51) in the group without sperm disappearance. There was a significant difference in carnitine content between pre-operation and postoperation (p lt 0.01). After RIOVD, the carnitine concentration in seminal plasma of the group with sperm disappearance was lower than that of the group without sperm disappearance (p lt 0.01). The results suggest that carnitine content in seminal plasma following RIOVD may be a reference index for judging the success or failure of the operation.