Platelet-directed antibody in the serum of patients with primary thrombotic thrombocytopenic purpura
Lazarchick, J.; Graddick, S.L.; Hall, S.A.; Genco, P.V.
Annals of Clinical and Laboratory Science 17(5): 339-344
1987
ISSN/ISBN: 0091-7370 PMID: 3314658 Document Number: 288336
Utilizing two platelet antibody assay systems, flow cytometric analysis and a microcytotoxicity assay, it was possible to demonstrate for the first time platelet-directed antibody in the sera of three of six patients with primary thrombotic thrombocytopenic purpura. These results lend support for an immune-mediated pathologic process in some patients with this disorder.