Changes in molecular markers in patients with thrombotic thrombocytopenic purpura
Takamatsu, J.
Nihon Rinsho. Japanese Journal of Clinical Medicine 51(1): 135-137
1993
ISSN/ISBN: 0047-1852 PMID: 8433505 Document Number: 409086
Hemostatic studies found in the patients with Thrombotic thrombocytopenic purpura were discussed. Most of them showed normal routine hemostatic studies; normal prothrombin time, activated partial thromboplastin time, plasma level of fibrinogen. Fibrin degradation products are more consistently abnormal, with approximately to 70% having slight elevations, but less than 25% of titers are greater than 25 micrograms/ml. Although some cases concerning of complication of disseminated intravascular coagulation in the patient with TTP are found in the literature, laboratory and clinical finding suggest that TTP and DIC are separate entities.