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Effect of cardiac glycosides on the calcium ion binding by biomembrane lipids

Ivanov, L.V.; Khadzhaĭ, I.I.; Chueva, I.N.; Makarevich, I.F.

Farmakologiia i Toksikologiia 50(2): 30-32

1987

ISSN/ISBN: 0014-8318
PMID: 3034664
Document Number: 287490
By using methods of fluorescent and spine (electron paramagnetic resonance) probes it was shown that cardiac glycosides (digoxin, digitoxin, convallatoxin, corelborine and strophanthin) effectively interact with biomembrane lipids enhancing conformational motility of lipids and cause additional binding of calcium ions with the membrane.

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