Type of behavior and superoxide dismutase activity in the brain of rats (a comparison of 2 Tryon strains)
Khonicheva, N.M.; Guliaeva, N.V.; Zhdanova, I.V.; Obidin, A.B.; Dmitrieva, I.L.
Biulleten' Eksperimental'noi Biologii i Meditsiny 102(12): 643-645
1986
ISSN/ISBN: 0365-9615 PMID: 3801607 Document Number: 283477
Differences in the type of behaviour in capable ("maze-bright") and incapable ("maze-dull") Tryon rats have been demonstrated in the situation with pain-irritated partner by the method of "emotional resonance". Most "bright" rats belonged to the type not avoiding the signals of another pain-irritated rat, they revealed a persistent ecologically defensive reaction of preferring a small closed space. The type of anxiety behaviour prevailed in the group of "dull" rats. In the open field test "bright" rats were characterized by low locomotor activity and high level of defecation and "dull" rats by high activity and low defecation. Increased levels of superoxide dismutase activity and high content of thiobarbituric acid-reactive material were observed in brains of dull rats. The interrelations between behavioural and molecular levels of defensive response to stress is discussed.