The effect of locally applied ipratropium aerosol on the nasal methacholine challenge in patients with allergic and non-allergic rhinitis
Sanwikarja, S.; Schmitz, P.I.; Dieges, P.H.
Annals of Allergy 56(2): 162-166
1986
ISSN/ISBN: 0003-4738 PMID: 2936282 Document Number: 282005
The effect of local pretreatment with ipratropium versus placebo aerosol on nasal methacholine challenge was studied in a double-blind, crossover trial. Fourteen allergic and ten non-allergic patients suffering from rhinitis participated in this study. It can be concluded that intranasal administration of ipratropium has a suppressive effect on hypersecretion and sneezing, but has no influence on nasal airway resistance.
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