Effect of irradiation on the size of isolated liver mitochondria
Avtandilov, G.G.; Sirotkin, V.V.; Dovzhenko, I.M.; Lobzin, A.P.
Biulleten' Eksperimental'noi Biologii i Meditsiny 101(4): 409-411
1986
ISSN/ISBN: 0365-9615 PMID: 3697486 Document Number: 281787
The role of external effects in the time course of changes in hepatocyte mitochondria size was studied. Suspensions of mitochondria isolated from the liver of inbred mice were investigated at various periods after gamma irradiation. Statistical analysis of changes in the size of isolated mitochondria has shown that irradiation leads to an increase in mitochondria size, reflected in the distribution pattern. The changes may be related to the functional activity, and distribution shifts may be regarded as manifestations of hepatocyte adaptation.