Clinical analysis of high grade bladder cancer
Miura, T.; Kubota, Y.; Ishibashi, Y.; Sakuramoto, T.; Noguchi, S.; Shuin, T.; Moriyama, M.; Hosaka, M.; Satomi, Y.; Fukushima, S.
Hinyokika Kiyo. Acta Urologica Japonica 32(6): 803-807
1986
ISSN/ISBN: 0018-1994 PMID: 3766339 Document Number: 281729
The prognosis and other clinical manifestation of 128 patients with high grade bladder tumor were analyzed. Thirty two percent of the total cases of bladder cancer were higher grade bladder cancer and 83% of their tumors were invasive tumor at stage T2 and worse. Urinary cytologies were positive in 88% of these patients. The 5-year survival rate in these patients was 32% and those in T1, T2 T3 and T4 cases were 64.2%, 55.6%, 22.7% and 8.0% respectively. The patients treated with radical (total) cystectomy showed a much better survival rate than the cases treated with TUR or partial cystectomy. These results suggest that high grade bladder cancers tend to be invasive and the patients with high grade bladder cancer would have a proper prognosis than the patients with other histological grade tumors. Thus, these patients should be treated more aggressively including radical cystectomy than the other cases of bladder cancers.