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Research on heterocyclic compounds. XIX--2-Methylimidazo[1,2-a]pyridine-3-acetic acids

Abignente, E.; Arena, F.; Luraschi, E.; Saturnino, C.; Marmo, E.; Russo, S.; Magliulo, R.

Il Farmaco; Edizione Scientifica 41(2): 119-130

1986

ISSN/ISBN: 0430-0920
PMID: 3486134
Document Number: 281235
A group of methyl substituted imidazo[1,2-a]pyridine-3-acetic acids was synthesized by reaction of some methyl derivatives of 2-aminopyridine with ethyl 3-bromolevulinate and subsequent hydrolysis. These new acidic compounds were tested for their antiinflammatory, analgesic, antipyretic and ulcerogenic activities in order to compare the results with those previously obtained with similar compounds.

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Abignente, E.; Arena, F.; De Caprariis, P.; Nuzzetti, R.; Marmo, E.; Lampa, E.; Rosatti, E.; Ottavo, R. 1981: Research on heterocyclic compounds. X.-Imidazo[1,2-a]pyrazine derivatives: synthesis and antiinflammatory activity Il Farmaco; Edizione Scientifica 36(1): 61-80
Abignente, E.; De Caprariis, P.; Luraschi, E.; Marmo, E.; Berrino, L.; Lo Sasso, C. 1989: Research on heterocyclic compounds. XXV. Phenyl derivatives of fused imidazole systems: antiinflammatory activity Research Communications in Chemical Pathology and Pharmacology 65(1): 35-56
Luraschi, E.; Arena, F.; Sacchi, A.; Laneri, S.; Abignente, E.; Avallone, L.; D'Amico, M.; Berrino, L.; Rossi, F. 1997: Research on heterocyclic compounds. XXXVIII. Synthesis and pharmacological activity of imidazo[1,2-b]pyridazine-2-carboxylic derivatives Farmaco 52(4): 213-217
Nacci, V.; Filacchioni, G.; Porretta, G.C. 1972: Research on compounds with psychotropic activity. I. Synthesis of 5-phenylpyrrolo-(2,1-d)(1,5)-benzothiazepin-6,6-dioxide and 1,2,3,3a,4,5-hexahydro-5-phenylpyrrolo-(2,1-d)(1,5)-benzothiazepin-1,4-dione-6,6-dioxide, derivatives of a new heterocyclic system Il Farmaco; Edizione Scientifica 27(11): 1003-1017
Schut, H.A.; Zu, H.X. 1993: Application of the 32P-postlabelling assay to the inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA adduct formation by dietary fatty acids Iarc Scientific Publications 124: 181-188
Guiotto, A.; Rodighiero, P.; Marciani Magno, S.; Gia, O.; Pastorini, G.; Manzini, P.; Zucca, M.; Viano, I. 1979: Bis-basic derivatives of planar heterocyclic compounds Il Farmaco; Edizione Scientifica 34(9): 774-788
Choisy, H.; Potron, G. 1971: Action of some heterocyclic nitro compounds on ethanol metabolism Therapie 26(6): 1219-1226
Pellicciari, R.; Curini, M.; Ceccherelli, P. 1977: Mass spectrometry of sulfurated heterocyclic compounds. Isothiochromanone and its derivatives Bollettino Chimico Farmaceutico 116(4): 229-238
Behera, R.K.; Dhal, P.N.; Nayak, A. 1981: Studies on heterocyclic compounds: Part I--Thiazole esters as anticholinergics Indian Journal of Biochemistry and Biophysics 18(3): 229-232
Hof, H.; Chakraborty, T.; Royer, R.; Buisson, J.P. 1987: Mode of action of nitro-heterocyclic compounds on Escherichia coli Drugs under Experimental and Clinical Research 13(10): 635-639
Il'iuchenok, T.I.; Frigidova, L.M.; Shadurskiĭ, K.S. 1980: Toxicity and radioprotective properties of heterocyclic compounds containing a hydrazine fragment Farmakologiia i Toksikologiia 43(6): 725-729
Phillips, J.C.; Bex, C.; Lake, B.G.; Cottrell, R.C.; Gangolli, S.D. 1982: Inhibition of dimethylnitrosamine metabolism by some heterocyclic compounds and by substrates and inhibitors of monoamine oxidase in the rat Cancer Research 42(9): 3761-3765
Kurtán, T.; Antus, S.án. 2003: Chiroptical study of O-heterocyclic compounds, secondary mono-alcohols and primary monoamines Acta Pharmaceutica Hungarica 73(3): 171-178
Bai, A.P.; Guo, Z.R.; Chu, F.M. 2001: Three dimensional quantitative structure-activity relationship of heterocyclic-compounds with di-tert-bultylphenyl inhibitors Yao Xue Xue Bao 36(5): 347-350
Bukowski, L.; Janowiec, M.; Zwolska-Kwiek, Z.; Andrzejczyk, Z. 1998: Some reactions of 2-cyanomethylimidazo[4,5-b]pyridine with isothiocyanates. Antituberculotic activity of the obtained compounds Die Pharmazie 53(6): 373-376
Chen, C.; Zheng, X.Y.; Zhu, P.E.; Guo, H.Z. 1982: Studies on new antimalarials--synthesis of heterocyclic compounds carrying double Mannich basic chains of p-aminophenol Yao Xue Xue Bao 17(2): 112-117
Picciòla, G.; Ravenna, F.; Carenini, G.; Manzardo, S.; Gentili, P. 1981: Heterocyclic compounds containing a 4-aminophenylalkanoic acid group with potential antiinflammatory activity. II. 2-Substituted morpholine derivatives Il Farmaco; Edizione Scientifica 36(1): 47-60
Adak, M.; Gupta, J.K. 2006: Hypolipidemic activity of Indan--1--acetic acids Nepal Medical College Journal: Nmcj 8(1): 22-26
Bukowski, L.; Janowiec, M. 1990: Synthesis and some reactions of 1-methyl-1H-2-cyanomethyl-imidazo[4,5-b]pyridine. Tuberculostatic activity of obtained compounds Die Pharmazie 45(12): 904-907
Hovell, F.D.; Greenhalgh, J.F. 1972: Utilization of salts of acetic, propionic and butyric acids by growing lambs Proceedings of the Nutrition Society 31(2): 68a