A case of CSF (colony-stimulating factor)-producing lung cancer and a review of the literature

Yoshihara, K.; Fukuyama, K.; Okamura, T.; Watanabe, S.; Sumida, I.; Hanada, M.; Nishihara, H.; Yoshihara, K; Fukuyama, K; Okamura, T; Watanabe, S; Sumida, I; Hanada, M; Nishihara, H

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A case of CSF (colony-stimulating factor) -producing lung cancer and a review of the literature

Yoshihara, K.; Fukuyama, K.; Okamura, T.; Watanabe, S.; Sumida, I.; Hanada, M.; Nishihara, H.

Gan no Rinsho. Japan Journal of Cancer Clinics 32(7): 805-809

1986

ISSN/ISBN: 0021-4949

PMID: 3016362

Document Number: 278744

A 36-year-old man with large-cell carcinoma of the lung showed marked leukocytosis of up to 109,300/mm3. As high CSF activity was detected in the pleural effusion and the supernatant of cell cultures originating from the effusion, a diagnosis of CSF-producing lung cancer was made. Twenty-one CSF-producing lung cancers have been reported in Japan. They comprised 13 large-cell carcinomas, six squamous cell carcinomas, one adenocarcinoma and one small cell carcinoma.