Attempt to modify Rauscher-virus leukemogenesis by modulation of lymphoreticular and hematopoietic tissue
Henkel, B.; Krueger, G.R.
Anticancer Research 6(4): 601-604
1986
ISSN/ISBN: 0250-7005 PMID: 3463240 Document Number: 273394
Rauscher erythroleukemia virus of the mouse was originally isolated from an animal bearing a lymphocytic neoplasm. In order to control extraneous influences on leukemia development, we modulated thymus-dependent and bursa-dependent lymphatic tissues and the granulopoietic and erythropoietic components of hemoreticular tissues during the latent period of leukemia development. In all experiments the same type of erythroleukemia was found with some variation in the course of the disease.