Morphology of the adrenal cortex in the adrenogenital syndrome with salt loss
Padalko, N.L.
Arkhiv Patologii 48(4): 51-56
1986
ISSN/ISBN: 0004-1955 PMID: 3718266 Document Number: 273180
Adrenals were studied in 17 children with adrenogenital syndrome with a salt loss. Adrenals from 9 children who died from mechanical asphyxia served as control. Adrenal weight, the width of adrenal zones were measured, the volumes of nuclei and nucleoli were calculated after having been drawn on millimeter paper. The dilatation of both fascicular and reticular zones, the persistence of a fetal zone were found. Nuclear polymorphism, hyperchromatism and in 2 cases-mitotic figures were observed in the fascicular zone. An increase of nuclear and nucleolar volume is noted in cells of glomerular and fascicular zones. The zones of an increased functional activity (inner part of a glomerular zone and external part of a fascicular one) are distinguished. Alterations if cortex cells are the evidence of their hypertrophy and, to a lesser extent, their hyperplasia.