The effect of heparin, prednisolone and triamterene on the elimination of India ink by the reticulohistiocyte system of the isolated perfused rat liver
Vömel, T.; Platt, D.; Pamler, B.
Arzneimittel-Forschung 36(9): 1353-1355
1986
ISSN/ISBN: 0004-4172 PMID: 3790185 Document Number: 272368
The influence of heparin, prednisolone and triamterene on the elimination of colloidal carbon (India ink) by the reticulohistiocytary system of the isolated perfused rat liver was measured. The drugs were given directly to the perfusion medium. A significant reduction of the phagocytic capacity of Kupffer's cells for colloidal carbon under the influence of heparin, prednisolone and triamterene could be demonstrated.
Document emailed within 1 workday
Related Documents
Joly, J.M.; Williams, W.M. 1991: Elimination of the antiviral drug 5-ethyl-2'-deoxyuridine by the isolated perfused rat liver Drug Metabolism and Disposition: the Biological Fate of Chemicals 19(6): 1058-1065Oie, S.; Fiori, F. 1985: Effects of albumin and alpha-1 acid glycoprotein on elimination of prazosin and antipyrine in the isolated perfused rat liver Journal of Pharmacology and Experimental Therapeutics 234(3): 636-640
Jones, D.B.; Morgan, D.J.; Mihaly, G.W.; Webster, L.K.; Smallwood, R.A. 1984: Discrimination between the venous equilibrium and sinusoidal models of hepatic drug elimination in the isolated perfused rat liver by perturbation of propranolol protein binding Journal of Pharmacology and Experimental Therapeutics 229(2): 522-526
Mechev, D.S.; Butsev, I.A. 1991: Reticulohistiocyte system activity of the liver in patients with nephrotuberculosis Vrachebnoe Delo 4: 29-31
Notter, D.; Roland, E. 1978: Localization of N-acetyltransferases in sinusoidal liver cells. Effect of zymosan on the acetylation of sulfamethazine and isoniazid in the rat and in isolated perfused liver Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 172(3): 531-533
Noguchi, Y.; Plaa, G.L. 1970: Effect of nucleotides and nitroglycerine on the hemodynamics of the isolated perfused rat liver Archives Internationales de Pharmacodynamie et de Therapie 188(2): 305-311
Macek, K.; Martínková, J.; Tilser, I. 1983: Influence of E2 and F2 alpha prostaglandins and of hydrocortisone premedication on the effect of adrenaline in the portal bed of isolated perfused rat liver Sbornik Vedeckych Praci Lekarske Fakulty Karlovy University V Hradci Kralove 26(2): 233-244
Heesen, W.F.; Beltman, F.W.; Smit, A.J.; May, J.F.; de Graeff, P.A.; Havinga, T.K.; Schuurman, F.H.; van der Veur, E.; Meyboom-de Jong, B.; Lie, K.I. 1998: Effect of quinapril and triamterene/hydrochlorothiazide on cardiac and vascular end-organ damage in isolated systolic hypertension Journal of Cardiovascular Pharmacology 31(2): 187-194
Grandjean, C.; Garcia, H. 1975: Studies on liver regeneration. Deoxyribonucleic acid synthesis in the isolated perfused liver after in vitro and in vivo partial hepatectomy Laboratory Investigation; a Journal of Technical Methods and Pathology 32(4): 552-554
Gascon-Barré, M.; Huet, P.M.; St-Onge-Brault, G.; Brault, A.; Kassissia, I. 1988: Liver extraction of vitamin D3 is independent of its hepatic venous or arterial route of delivery. Studies in isolated-perfused rat liver preparations Journal of Pharmacology and Experimental Therapeutics 245(3): 975-981
Ramsöe, K.; Juul-Nielsen, J.; Hansen, R.I.; Schmidt, A.; Winkler, K.; Tygstrup, N. 1971: The functional pattern of the isolated perfused pig liver Scandinavian Journal of Gastroenterology. Suppl 9: 149-154
Abadìa, A.R.; De Francesco, L.; Guaitani, A. 1995: Disposition of ciprofloxacin in the isolated perfused rat liver Drug Metabolism and Disposition: the Biological Fate of Chemicals 23(2): 197-200
Tygstrup, N.; Funding, J.; Juul-Nielsen, J.; Keiding, S.; Koudahl, G.; Ramsöe, K.; Winkler, K. 1971: The function of the isolated perfused and the in vivo pig liver Scandinavian Journal of Gastroenterology. Suppl 9: 131-138
Cordone, A.; Fugassa, E.; Gallo, G.; Voci, A. 1980: Characteristics of synthesized RNA in the isolated and perfused rat liver Bollettino della Societa Italiana di Biologia Sperimentale 56(4): 295-301
Massari, N.; Tenconi, L.; Civardi, F.; Santambrogio, C.; Negri, S.; Procaccia, S.; Samaja, U. 1970: Methods of investigations of "functionality" of the isolated and perfused liver Minerva Medica 61(56): 3121-3126
Lemberg, A.; Wikinski, R.; Izurieta, E.M.; Halperin, H.; Freid, A.; Krasnokuki, D.; Perez de Neuman, P. 1970: Action of the isolated perfused rat liver on hyperlipemic serum Medicina 30(2): 153-156
Liao, J.; Keiser, J.A.; Scales, W.E.; Kunkel, S.L.; Kluger, M.J. 1995: Role of epinephrine in TNF and IL-6 production from isolated perfused rat liver American Journal of Physiology 268(4 Pt 2): R896-R901
Shattuck, K.E.; Grinnell, C.D.; Keeney, S.E.; Noworyta, K.; Rassin, D.K. 1997: Hyperoxia and glutathione depletion in the isolated perfused rat liver Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research 45(9): 576-583
Dong, S.N.; Bai, F.; Yang, H.J.; Lou, Y.Q.; Liang, W.S. 1989: Studies on the metabolism of antiepilepserine in isolated perfused rat liver Yao Xue Xue Bao 24(4): 241-245
Liao, J.; Keiser, J.A.; Scales, W.E.; Kunkel, S.L.; Kluger, M.J. 1995: Role of corticosterone in TNF and IL-6 production in isolated perfused rat liver American Journal of Physiology 268(3 Pt 2): R699-R706