Morphological characteristics of the sequelae from the parenteral administration of solutions of hydroxyethyl starch
Prostakova, T.M.; Glasko, E.N.; Khokhlova, M.P.; Polushina, T.V.
Arkhiv Patologii 48(7): 43-47
1986
ISSN/ISBN: 0004-1955 PMID: 2428336 Document Number: 271929
Rats and rabbits were infused with solutions of hydroxyethyl starch (HES) with different physical and chemical properties. Large quantities of HES produced specific macrophage reaction in the spleen. When used in therapeutic doses (plasmaexpander) HES caused no macrophage reaction. HES proved to be non-toxic for the internal organs.